Medicare and Medicaid

CMS finalizes 340B payment cuts and expanded site-neutral Medicare payments

Medicare will reimburse 340B participants at average sales price minus 28%, while expanding equal payments for some imaging services.

Reported by 3 outlets Thursday, November 5, 2026

An empty hospital corridor
Photo: CC0, Carol M. Highsmith, Library of Congress

CMS finalized its 2027 outpatient payment rule, cutting Medicare payments for drugs acquired through the 340B program and expanding site-neutral payments. Hospital outpatient departments and ambulatory surgery centers will receive a 2.3% payment increase next year, below the 2.4% increase regulators proposed.

Under the rule, Medicare will reimburse 340B participants at the drug’s average sales price minus 28%. CMS said the change would reduce drug spending by about $5.5 billion next year. The rule also sets the same payment rate for imaging services without contrast at hospital outpatient departments and freestanding physician offices.

CMS estimates the site-neutral policy will save taxpayers and beneficiaries over $9 billion over a decade. The American Hospital Association said the payment increase would not address hospitals’ financial challenges and warned that the 340B changes would add stress.

Reporting on this story

More top stories

This Week in Medicine

The week in medicine, in five minutes

The most important medical news of the week, summarized for you and easy to read. Every Sunday, free.

Free. No spam. Unsubscribe anytime.