Industry

Setara launches with $90 million to develop rare-disease drugs

Setara raised $90 million to advance STAR-0871, which it plans to study in Charcot-Marie-Tooth disease and overactive bladder.

Reported by 2 outlets Sunday, November 1, 2026

A gloved hand using a pipette in a laboratory
Photo: Public domain

Setara Biosciences launched with $90 million in Series A funding to advance drug programs spun out of Actio Biosciences, MedCity News reported. The company’s lead program, STAR-0871, is a small molecule being developed for Charcot-Marie-Tooth disease type 2C and overactive bladder.

A Phase 1 trial of the drug was already underway, and Setara said the healthy volunteer portion is complete. MedCity News reported that Setara plans to expand the study to a Phase 1b study enrolling patients with Charcot-Marie-Tooth next year. The company also plans a separate Phase 2a trial in overactive bladder.

Investors include Actio backers Deerfield Management, Canaan, Droia Ventures, EcoR1, Euclidean Capital and Regeneron Ventures. Jazz Pharmaceuticals also invested in Setara.

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